Investigation of the Relationship between Metal Concentrations in Welding Fumes and Toenails for Biomonitoring Chronic Exposures

Chang Geun Lee

Welding, soldering, and brazing workers are a critical part of the US workforce, with over 574, 000 employees in 2020. Unfortunately, these workers are frequently exposed to welding fumes that contain metallic particles such as chromium, copper, manganese, iron, and nickel, which can lead to serious adverse health effects such as lung disease, Parkinson-like symptoms, and metal fume fever. However, the dose-response of different metals in a chronic exposure setting is not fully understood. Therefore, the development of a biomarker to assess chronic exposure is critical for assessing potential health risks. This study aims to investigate the use of toenail metal concentrations as biomarkers for chronic exposure to metals.

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